When recently widowed Katherine Samuals purchases a home to share with her son, Christopher, and best friend, Denise Richards, the last thing she expects is to include Denise's outrageous sister, Darla Richards, into the household. But Katherine agrees because she adores Darla's daughter, Chelsea, and feels this is a good opportunity to give the young teen a real home.

Living with Darla is not easy. She parties too much, sleeps around, and speaks her mind without apology. To conservative Katherine and shy Denise, Darla’s behavior is intolerable. Then, Darla is diagnosed with AIDS, and the household is turned upside-down. Katherine finds herself thrown into Darla's life, first as her caregiver, then as her companion as she explores the devastating lives of AIDS sufferers. Katherine's fledgling writing career flourishes as she shares the experiences of Darla's AIDS group in newspaper articles across the country. And Denise finds true love for the first time, but struggles with the inappropriate timing of her personal happiness. Surprisingly, Darla also finds love−real love−in a time when she needs it the most.

As the household struggles with the stress of living with a terminal illness, Katherine, Denise, and Darla learn just how strong their bond of friendship, and sisterhood, is.

If you are a sister or best friend, you will love this story.